awwww-cute:

Such ferocity!

awwww-cute:

Such ferocity!

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syfycity:

Why So Many Nerds Have Allergies

syfycity:

Why So Many Nerds Have Allergies

space-grunge:

space-grunge:

☹ SPACETRASH x SPACE-GRUNGE GIVEAWAY 

☯ I recently reached 45k followers, so it’s time for a giveaway in collaboration with me and my boyfriend’s Etsy shop: SPACETRASH!

☯ Reblog this post to win a $50 giftcard to SPACETRASH

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☯ Winner will be announced on 4/20!

☯ You can reblog this as many times as you want.

P.S. If you aren’t feeling lucky, you can shop our store now and use coupon code FESTBEST14 for 25%. Code ends on 4/20/14/

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power, speed, agility

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color-division:

Is like one of my Hannigram fics"  you whispered as you watched Su-zakana, no, wait! this show IS a Hannigram fic

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bpod-mrc:

20 April 2014
Nuclear Deterioration
In the long-running investigation into the causes of Parkinson’s disease, scientists have a new lead: defects in the nuclei of brain-cell precursors. Post-mortem analysis of brain tissue from Parkinson’s patients revealed a high proportion of neurons [nerve cells] with deformed nuclei, suggesting nuclear deterioration plays a role in the disease. Researchers suspect the distortion might be caused by mutation in the LRRK2 gene that correlates with Parkinson’s, so they put the theory to the test. As induced pluripotent stem cells derived from patients became brain-cell precursors, nuclear architecture slowly deteriorated until they were clearly misshapen (pictured right) compared to healthy controls (left). The mutant cells also failed to mature into neurons. When the LRRK2 mutation was corrected, however, nuclei developed normally. Treating the brain-cell precursors with a particular compound achieved the same result, raising the possibility of a drug to reverse the problem and treat the disease.
Written by Daniel Cossins
—
Image courtesy of Juan Carlos Izpisua Belmonte and colleaguesThe Salk Institute for Biological Studies, USA Copyright held by original authors Research published in Nature, November 2012
—
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bpod-mrc:

20 April 2014

Nuclear Deterioration

In the long-running investigation into the causes of Parkinson’s disease, scientists have a new lead: defects in the nuclei of brain-cell precursors. Post-mortem analysis of brain tissue from Parkinson’s patients revealed a high proportion of neurons [nerve cells] with deformed nuclei, suggesting nuclear deterioration plays a role in the disease. Researchers suspect the distortion might be caused by mutation in the LRRK2 gene that correlates with Parkinson’s, so they put the theory to the test. As induced pluripotent stem cells derived from patients became brain-cell precursors, nuclear architecture slowly deteriorated until they were clearly misshapen (pictured right) compared to healthy controls (left). The mutant cells also failed to mature into neurons. When the LRRK2 mutation was corrected, however, nuclei developed normally. Treating the brain-cell precursors with a particular compound achieved the same result, raising the possibility of a drug to reverse the problem and treat the disease.

Written by Daniel Cossins

Image courtesy of Juan Carlos Izpisua Belmonte and colleagues
The Salk Institute for Biological Studies, USA
Copyright held by original authors
Research published in Nature, November 2012

You can also follow BPoD on Twitter and Facebook

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umm excuse me avatar I see a little more than four elements 

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